Endocrine Abstracts

Evidence from studies in goats1, sheep2 and mice3 suggests that the kisspeptin cells of the arcuate nucleus generate the signal that causes the pulsatile secretion of GnRH. This effect may be due to action of kisspeptin on GnRH terminals in the median eminence3,4. We conducted studies on sheep to test the hypothesis that kisspeptin cells of the arcuate nucleus (ARC) and/or the glutamate cells of the hypothalamus pulses of GnRH secret...

Introduction: Bardet–Biedl syndrome is a rare autosomal recessive disorder with a wide range of clinical features. The primary clinical features include rod-cone dystrophy, postaxial polydactyly, central obesity, cognitive impairment, male hypogonadism and renal dysfunction.Case report: 22 Year old male, mentaly retarded with Bardet Biedle syndrome presented to our ER with vomiting and generalized weakness for 1 week. There was no history of fever, ...